Cancer Discussions, Cancer Treatment Options Forum - February 15th, 2010 - 4 Comments
Should a woman be tested to see if she has a P53 mutation after having had chemo for breast cancer?
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Recently it was discovered that having a healthy P53 gene may actually cause cancer cells to grow back after chemo. A certain mutation will not cause regrowth of cancer cells. Should one be tested to see if the gene has mutated or not?
The mutation appears to improve survival rates. But does knowing whether or not you have the mutation change any thing in regards to treatment? Anyone have an answer?
Thank you.


There is really no definitive answer. There have been studies and clinical trials and nothing has been approved yet. Believe me, between what my job is and the fact that I am a breast cancer survivor, I keep a very close eye on issues like this.
Would it change treatment? Not as of right now. But it’s something you should discuss with your oncologist-if you have one. I am due for my routine check-up in September. I will discuss it with her–whether anything else is discovered by then or not.
**And, obviously, the guy below doesn’t know his BUTT from a hole in the ground.
BEtter be safe than sorry!!!! check everything! women have to take a lot of crap in life and they have to give birth and be nice or be mistaken for a man and so we need to make sure when they are in trouble you make them better do whatever you can. and when they pass on be happy but dont make any graven idols1
Dear madam, instead of having preoccupations of these molecule-sized thoughts, you’d better to consider regular exercise, low fat and sugar regimes, forgetting about smoking and eating more and more fresh vegetables and fruits. By this way your P53 works properly.
As a breast cancer survivor you have my sincere sympathies. Don’t know the answer to your question but when you do find out please publish it for the rest of us.
Message to R.T. Your message was completely out of order, how dare you suggest your witch doctor medicine to someone who has cancer. I hope you are never unfortunate enough to be diagnosed with this awful disease. Don’t ever forget these words and be careful how you reply to sick people in the future. Big brother may just be watching you.